The Soul Stone in Vormir became concealed in a shrine, accessible only to those who were willing to sacrifice someone that they loved.
Red Skull: Soul holds a special place among the Infinity Stones. You might say, it is a certain wisdom.
Thanos: Tell me what it needs.
Red Skull: To ensure that whoever possesses it understands its power, the stone demands a sacrifice...In order to take the stone, you must lose that which you love. A soul for a soul.
In the events of Avengers: Infinity War we see that Thanos gets the Soul Stone by sacrificing the daughter he loved most.
If someone defeats Thanos, does he/she automatically get the Soul Stone or will they still have to sacrifice someone they loved?