In Prison Break, why was Michael's mother so ruthless and why did she want to kill Michael?
Christina Scofield was not trying to kill Michael at all. But she wanted to access Scylla. Michael and team in the process of getting clemency for everyone stole Scylla from The Company after which it somehow landed in hands of Christina Scofield. Which was again stole by Michael. Christina then kidnaps Lincoln and shoots him.
Michael being close to Lincoln from childhood had gone through so much that he doesn't feels much emotions towards his mother who lied and went away while he was young.
Hence Michael first tries to kill Christina himself and then through Mahone, but she survives and then she try to kill him but Sara gets her first.