In Breaking Bad, Season 2, later on after giving the 480K to Jesse, Walt goes round to his house once more and finds Jesse high, asleep next to Jane, then witnesses her throwing up and choking to death.
Before letting himself into the house though, while knocking on the door, he repeatedly says "Jesse I just want to talk".
What did Walt want to discuss at that point ?
Walt had an argument with Jesse... Well, actually it was Jane who had tried to blackmail Walt into giving Jesse the $480K. But there had been a strain on Walt and Jesse's relationship for a while.
So, if you recall, after Walt drops off the money to Jesse and Jane, he goes to a bar and coincidentally runs into Donald, Jane's father. They begin talking about family, not knowing their lives are intertwined, and Donald makes a remark about never giving up on family. Walt had gone back to talk to Jesse, to smooth things over, and when he saw Jane in the throes of death he pretty much knew the best solution was to get her out of the picture.
