Marvel hasn't up to now held the tv shows to be completely cannon simply because of the effort of arranging the appropriately time plot crossing. I recall Agents of Shield taking a brief hiatus because it's next episode was going to impinge on Thor 2.
There was references to the war on New York and the aftermath. Some of the shorts made around that time connected shield cleanup operations of alien weapons with the plot. After Thor, the entire team was diverted to London to reclaim potentially dangerous or contaminated alien debris. The fall of SHIELD Captain America led directly to the plot to bring back shield.
The Netflix shows referred to the movies events as well. Kingpin was making a lot of money reclaiming and rebuilding destroyed New York. A lot of small operators were scavenging. One of those ran into damage control who seized all the potential profits, tying all that into the Spiderman plot.
Some of SHIELD's adventures won't happen for hundreds of years, others involve other realities or computer simulations.
Given the rifts in reality Wanda appears to be about to produce, with rumors of multiversal crossovers from various stars I suspect it'll all be cannon, somewhere, so long as you know what universe you're talking about. Like one of the ones with Loki and the tesseract running free. Or where where wolverine is a key player in the X-Men. One where Wanda meets Pietro, just not hers, etc.