During Iron Man 2, the Stark Expo is pretty clearly modeled on the New York World's Fair grounds. Tony and Happy are able to drive from Stark Expo to Washington D.C. in a few hours (at most, overnight). And late in the film, when tracing Vanko's phone call to Stark, the trace shows the call get traced to Hammer Industries in New York City. Meanwhile, it's already established that Stark lives in Malibu, and much of the film occurs at his house.
There's no indication that there's a large distance between Stark Expo, Hammer Industries, and Stark's home. But there are implied vast distances between some of these locations. Where did the film take place? Is it supposed to have taken place on both the East and West coasts?