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Melfi has a history of alcohol abuse. Kupferberg is aware of this and is afraid that Melfi might use alcohol to escape her guilt about abandoning Toni. He uses the term sugar substitutes as a euphemism for alcohol. Alcohol is not a sugar in the chemical sense, but rather a product of fermenting sugar. It can however, toxic effects left aside, serve as a ...


I don't think he's hinting at anything but rather advising Melfi about her health. Sugar substitutes (AKA sweeteners) might be as detrimental to your health as sugar and might lead to weight gain.* From the Wikipedia page about sugar substitutes: A 2012 study at Universidade Federal do Rio Grande do Sul showed that addition of either saccharin or ...

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