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Without thinking too detailed into it, there is no real origin other than communication itself. The spreading of a message, that is the communication and or miscommunication of information can lead to different results. A guess could be Montreal, where English-speaking Canadians and French-speaking Canadians reside and how hard it is to interact. Another ...

Short version: The virus evolved from the dialogue Mazzy gave over the radio, as heard in the opening credits of the movie, and as shown visually as “typo” becomes “Pontypool”. Mazzy is the source and the vector – who spread it over the radio to the local community. Long version: In the book (originally a radio play) the name of the disease is Acquired ...