House (also known as House, M.D.) is an American television medical drama about Dr. Gregory House, a pain medication-dependent, unconventional, misanthropic medical genius who leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
I realize this may be a reach, but I noticed something odd in season 1 of House: In episode 15, there was a mention of Des Moines (Iowa). House: You’re worried about how his coworkers will react ...
Sometimes directors/creators of TV series will throw in Easter eggs of something they like, where they're from etc. For example, in Seinfeld there's quite a few episodes with some sort of Superman ...