House (also known as House, M.D.) is an American television medical drama about Dr. Gregory House, a pain medication-dependent, unconventional, misanthropic medical genius who leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

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What was the “It Could Be” running joke on House MD?

On House, MD, there was a running gag were for every case, someone would suggest that it could be a specific disease but it never was (I can’t remember if it ever turned out to be the case). I knew ...