Was there any significance to Wil Wheaton being in the theater to watch Star Wars with Koothrapali, Leonard, and Howard, while wearing a Star Fleet uniform in The Big Bang Theory episode "The Opening Night Excitation"?
The plot and dialog from the episode answer this. Wil Wheaton is a troll, and enjoys messing with people (remember the bowling games?). And he's most known for playing Wesley on Star Trek TNG. The Trekkie vs Jedi (Star Trek vs Star Wars fans) feud is as famous as the Hatfields and McCoys (No, not that McCoy.)
From the transcript:
Someone should have told him to "Shut Up, Wesley", that really pisses him off (in real life):
Wil Wheaton played Wesley Crusher on Star Trek: The Next Generation.
It's a simple joke that despite seeing Star Wars, he's wearing his Star Trek uniform instead.