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A teenager is diagnosed with an extremely rare aging syndrome /disease. Not progeria, makes him get gray hair and wrinkles and look like a 60 year-old when he's 16. I think he takes a plane trip to reconnect with some people before he dies.

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Do you remember any other details and why you thinks its not progeria? –  Ankit Sharma Jan 16 at 7:26
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The Three Wishes of Billy Grier (1984) - Movie Poster

Your movie could be this:

The Three Wishes of Billy Grier (1984)

Here's the trailer, and below, an excerpt from the movie's Wikipedia page:

Ralph Macchio plays Billy Grier, the 15-year-old victim of a rare degenerative disease that speeds up the aging process. After Billy suddenly becomes ill, a series of tests are run, with the diagnosis tragic. A team of doctors tell Billy and his mother Nancy (Betty Buckley) that there is no cure for his condition and that he will die of old age related natural causes decades before his time...

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